Club Deportivo San Isidro is a Spanish football club based in Granadilla de Abona in the Canary Islands. They currently feature in the Preferente de las Islas Canarias.
CD San Isidro were established in 1970 and started life in the Preferente de las Islas Canaries. They gained promotion from the Tercera DIvision to the Segunda Division B for the 2005-2006 season but could not stay there much longer.
CD San Isidro play their home matches at La Palmera that can accommodate 2,700 spectators.