Southampton host Arsenal in the pick of the FA Cup fourth round fixtures on Saturday, while Manchester City go to fourth tier Cheltenham Town.
The Gunners have hit form over the past month, including five wins from their past six games where they’ve been unbeaten.
Arsenal have a few injury worries too, with Dani Ceballos and Pablo Mari no certainties to take their places.
“Left calf. Missed Monday’s match against Newcastle United as a precaution with tight calf,” the club said in a statement.
“Dani will continue to be assessed in the coming days and will be tested ahead of Saturdays match.
On Pablo Mari, “Right calf. Pablo is progressing well from a mild calf strain. Aiming to be back in training next week.”
Southampton will definitely be without Jannik Vestergaard due to a knee problem, while gun forward Danny Ings is in doubt too.
Manchester City have been in excellent form in the top flight too, winning their past nine consecutive games.
They’ll have to do without Kevin De Bruyne who has a muscular complaint and will miss the next six weeks in a major blow.
“You have to know that I am going to miss Kevin a lot,” City boss Pep Guardiola.
“He is almost irreplaceable for the quality he has. He was nominated the best player in Premier League last season.
We know how good he is. At the same time, we have to find replacements while he is out.”
Elsewhere, Brighton host Blackpool, West Ham United entertain Doncaster Rovers and Sheffield United welcome Plymouth Argyle.