Once again, Daisuke Matsusaka failed to impress in 6 innings of work, giving up 5 runs, 2 of them in the first inning.
Boston answered back with 4 in the 4th, only to see the Jays take the lead with runs in the 4th and 6th.
Coco Crisp tied the game with a home run in the 7th, and three innings ater the rookie Jed Lowrie gave his team the win, with the win going to Jonathan Papelbon.
There was some stellar defense played, particularly by the Red Sox. Jason Bay made a spectacular catch against the left field wall that saved a triple in the bottom of the 10th.
Earlier in the game, Jacoby Ellsbury ran into a chain link face, cutting his face, but nevertheless held onto a ball hit by Adam Lind.
The Red Sox had other heroes, of course. Dustin Pedroia continued his hot hand by hitting a 3-run homerun in the 4th that initially gave the Sox the lead.
The Sox have Monday off before opening a 3-game series with the New York Yankees at Yankee Stadium.